+20 Questions on Cell Cycle
20 multiple-choice questions with five alternatives (A–E) on the Cell Cycle, each numbered and followed by the answer key at the end.
Multiple-Choice Questions: Cell Cycle
1. Which of the following correctly represents the sequence of events in the cell cycle?
A) G1 → G2 → M → S
B) S → G1 → G2 → M
C) G1 → S → G2 → M
D) M → G1 → S → G2
E) G2 → S → G1 → M
2. What happens during the G1 phase of the cell cycle?
A) DNA replication
B) Cell growth and normal functions
C) Chromosome separation
D) Cytokinesis
E) Nuclear envelope breaks down
3. What does the "S" phase of the cell cycle stand for?
A) Synthesis of proteins
B) Separation
C) Structure formation
D) Synthesis of DNA
E) Synthesis of ATP
4. Which phase of the cell cycle involves cell division?
A) S phase
B) Interphase
C) M phase
D) G1 phase
E) G2 phase
5. Which of the following is not part of interphase?
A) G1
B) S
C) M
D) G2
E) All are part of interphase
6. In which phase of the cell cycle is DNA replicated?
A) G1
B) S
C) G2
D) M
E) Cytokinesis
7. During which phase does the cell prepare for mitosis by producing proteins and organelles?
A) G1
B) S
C) G2
D) M
E) Telophase
8. What process directly follows mitosis in the cell cycle?
A) Interphase
B) Synthesis
C) G2
D) Cytokinesis
E) Apoptosis
9. Which phase of the cell cycle is the longest?
A) M phase
B) Cytokinesis
C) Interphase
D) Anaphase
E) Telophase
10. What regulates the progression of cells through the cell cycle?
A) ATP
B) Chromatin
C) Cyclins and CDKs
D) Glucose
E) Enzymes
11. What happens during the M phase of the cell cycle?
A) Growth of the cell
B) DNA replication
C) Cell division (mitosis and cytokinesis)
D) Cell rest
E) DNA damage repair
12. When do cells check for DNA damage before division?
A) During cytokinesis
B) At the G1 checkpoint
C) At the M phase
D) During metaphase
E) At the telophase
13. Which checkpoint verifies that DNA has been completely and correctly replicated?
A) M checkpoint
B) S checkpoint
C) G2 checkpoint
D) Cytokinesis checkpoint
E) Telophase checkpoint
14. What is the role of the spindle checkpoint during mitosis?
A) To start DNA replication
B) To check chromatin structure
C) To ensure chromosomes are aligned properly
D) To activate cyclins
E) To repair organelles
15. What is apoptosis?
A) Cell division
B) DNA replication
C) Programmed cell death
D) Cytokinesis
E) Cell wall synthesis
16. Which of the following cells typically remain in the G0 phase permanently?
A) Liver cells
B) Muscle cells
C) Skin cells
D) Blood cells
E) Epithelial cells
17. Which type of macromolecule are cyclins?
A) Lipids
B) Proteins
C) Carbohydrates
D) Nucleic acids
E) Steroids
18. Which event marks the end of the M phase?
A) DNA synthesis
B) Disappearance of the nuclear membrane
C) Chromosome alignment
D) Cytokinesis
E) Start of interphase
19. What happens to the nuclear envelope during mitosis?
A) It thickens
B) It stays intact
C) It dissolves in prophase and reforms in telophase
D) It merges with the cell membrane
E) It breaks during cytokinesis only
20. What happens if the cell cycle is not properly regulated?
A) Apoptosis always occurs
B) The cell becomes inactive
C) The cell may become cancerous
D) The nucleus disappears
E) The cell transforms into a gamete
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Answer Key
1. C
2. B
3. D
4. C
5. C
6. B
7. C
8. D
9. C
10. C
11. C
12. B
13. C
14. C
15. C
16. B
17. B
18. D
19. C
20. C
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