Questions About Skeletal Diseases
Multiple-Choice Questions: Skeletal Diseases
1. Which disease is characterized by the progressive loss of bone mass and density?
A) Arthritis
B) Osteoporosis
C) Scoliosis
D) Rickets
E) Bursitis
2. What is the main cause of rickets in children?
A) Iron deficiency
B) Bacterial infection
C) Vitamin D deficiency
D) Lack of protein
E) Overexposure to sunlight
3. Which condition involves the inflammation of joints?
A) Osteomyelitis
B) Scoliosis
C) Arthritis
D) Osteopenia
E) Gout
4. Scoliosis is best described as:
A) A fracture of the spine
B) Inflammation of the knee joint
C) A curvature of the spine
D) Dislocation of the vertebrae
E) Deformation of the skull
5. Which skeletal disease is autoimmune in origin and affects joints symmetrically?
A) Osteoarthritis
B) Gout
C) Fibromyalgia
D) Rheumatoid arthritis
E) Bursitis
6. Osteomyelitis refers to:
A) Degeneration of cartilage
B) Inflammation of the bone due to infection
C) Overgrowth of bone tissue
D) Bone cancer
E) Fracture of long bones
7. Which of the following can lead to osteoporosis?
A) Excessive calcium
B) Increased bone formation
C) Sedentary lifestyle and low calcium intake
D) Excessive weight lifting
E) Viral infection
8. What is a common symptom of osteoarthritis?
A) Rash
B) Joint pain and stiffness
C) Seizures
D) Fever
E) Skin ulcers
9. Which of these skeletal conditions is caused by uric acid buildup in joints?
A) Osteoporosis
B) Arthritis
C) Scoliosis
D) Gout
E) Spina bifida
10. What is the most common bone cancer in children?
A) Myeloma
B) Chondrosarcoma
C) Osteosarcoma
D) Fibrosarcoma
E) Lymphoma
11. Which test is commonly used to diagnose bone density?
A) ECG
B) MRI
C) X-ray
D) DEXA scan
E) PET scan
12. What is the condition in which bones become soft due to vitamin D deficiency in adults?
A) Osteopenia
B) Osteomyelitis
C) Osteosarcoma
D) Osteomalacia
E) Scoliosis
13. A herniated disc affects which part of the skeletal system?
A) Femur
B) Skull
C) Ribcage
D) Vertebral column
E) Pelvis
14. What condition is associated with bone pain, fractures, and skeletal deformities due to abnormal bone remodeling?
A) Paget’s disease
B) Rickets
C) Gout
D) Lupus
E) Fibromyalgia
15. Which of the following is not a skeletal disease?
A) Osteoarthritis
B) Osteoporosis
C) Tendonitis
D) Rheumatoid arthritis
E) Osteomalacia
16. Which skeletal condition can result from menopause in women due to decreased estrogen levels?
A) Osteosarcoma
B) Osteomyelitis
C) Osteoporosis
D) Scoliosis
E) Arthritis
17. What is kyphosis?
A) Sideways curvature of the spine
B) Backward curvature of the knees
C) Forward rounding of the upper back
D) Inflammation of the vertebrae
E) Bone infection
18. Ankylosing spondylitis primarily affects:
A) Skull bones
B) Finger joints
C) Spine and sacroiliac joints
D) Ribcage
E) Pelvic floor muscles
19. What type of arthritis is most associated with wear and tear of cartilage?
A) Psoriatic arthritis
B) Rheumatoid arthritis
C) Gout
D) Septic arthritis
E) Osteoarthritis
20. What is the main mineral that bones lose in osteoporosis?
A) Iron
B) Potassium
C) Phosphorus
D) Magnesium
E) Calcium
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Answer Key with Explanations
1. B) Osteoporosis – Leads to brittle, porous bones and increased fracture risk.
2. C) Vitamin D deficiency – Causes poor calcium absorption, leading to rickets.
3. C) Arthritis – General term for joint inflammation.
4. C) A curvature of the spine – Lateral bending of the spinal column.
5. D) Rheumatoid arthritis – Autoimmune condition affecting synovial joints symmetrically.
6. B) Inflammation of the bone due to infection – Often bacterial and painful.
7. C) Sedentary lifestyle and low calcium intake – Major contributors to bone thinning.
8. B) Joint pain and stiffness – Especially after activity or in the morning.
9. D) Gout – Uric acid crystals accumulate in joints, causing pain and swelling.
10. C) Osteosarcoma – Aggressive bone cancer, common in children and teens.
11. D) DEXA scan – Dual-energy X-ray absorptiometry; measures bone density.
12. D) Osteomalacia – Softening of adult bones, typically due to vitamin D deficiency.
13. D) Vertebral column – Involves disc rupture pressing on nerves.
14. A) Paget’s disease – Disorganized bone remodeling leads to deformities.
15. C) Tendonitis – Involves tendons, not bones or joints directly.
16. C) Osteoporosis – Linked to reduced estrogen after menopause.
17. C) Forward rounding of the upper back – Hunchback appearance.
18. C) Spine and sacroiliac joints – Chronic inflammatory disease of axial skeleton.
19. E) Osteoarthritis – Caused by mechanical wear and degradation of cartilage.
20. E) Calcium – Its loss weakens bones in osteoporosis.
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