Questions on Muscles System, Skeletal Muscles, and Muscle Contraction
Multiple-Choice Questions: Muscles, Skeletal Muscles, and Muscle Contraction
1. What is the primary function of skeletal muscles?
A) Pump blood
B) Generate hormones
C) Provide movement
D) Transport oxygen
E) Digest food
2. Which type of muscle is voluntary and attached to bones?
A) Smooth muscle
B) Skeletal muscle
C) Cardiac muscle
D) Involuntary muscle
E) Tendon
3. Muscle contraction is primarily triggered by the release of:
A) Sodium ions
B) Calcium ions
C) Potassium ions
D) Glucose
E) Oxygen
4. The basic contractile unit of a muscle fiber is called a:
A) Myofibril
B) Sarcomere
C) Actin
D) Myosin
E) Muscle spindle
5. Which of the following proteins is responsible for the thick filament in muscle fibers?
A) Actin
B) Troponin
C) Tropomyosin
D) Myosin
E) Collagen
6. What connects muscle to bone?
A) Ligaments
B) Cartilage
C) Tendons
D) Nerves
E) Discs
7. Which structure stores calcium in muscle cells?
A) Nucleus
B) Golgi apparatus
C) Mitochondria
D) Sarcoplasmic reticulum
E) Ribosomes
8. Muscle fatigue is most often caused by a lack of:
A) Water
B) Protein
C) Oxygen
D) ATP
E) Calcium
9. Which of the following is not a type of muscle tissue?
A) Skeletal
B) Cardiac
C) Connective
D) Smooth
E) All are types
10. Which muscle type is found in the walls of hollow organs and is involuntary?
A) Skeletal
B) Cardiac
C) Smooth
D) Voluntary
E) Somatic
11. What neurotransmitter is released at the neuromuscular junction to initiate muscle contraction?
A) Dopamine
B) Serotonin
C) Acetylcholine
D) Epinephrine
E) Histamine
12. What is the name of the membrane that surrounds an individual muscle fiber?
A) Perimysium
B) Epimysium
C) Endomysium
D) Sarcolemma
E) Sarcoplasm
13. Which of the following is true about cardiac muscle?
A) Voluntary and multinucleated
B) Involuntary and striated
C) Found in hollow organs
D) Controlled consciously
E) Regenerates rapidly
14. What causes the striated appearance in skeletal muscle fibers?
A) Smooth sarcoplasm
B) Nuclei
C) Intercalated discs
D) Alternating actin and myosin bands
E) Mitochondrial arrangement
15. Which of the following terms describes a sustained muscle contraction without relaxation?
A) Twitch
B) Spasm
C) Tetanus
D) Isotonic
E) Reflex
16. The sliding filament theory describes the interaction between:
A) Sarcoplasm and mitochondria
B) Troponin and tropomyosin
C) Myosin and actin
D) ATP and calcium
E) Axons and dendrites
17. Which of the following is responsible for breaking down acetylcholine in the synaptic cleft?
A) ATP
B) Creatine kinase
C) Acetylcholinesterase
D) Calcium
E) Tropomyosin
18. What energy molecule is most directly used during muscle contraction?
A) Glucose
B) ADP
C) Creatine
D) ATP
E) Glycogen
19. Which of these structures is the outermost connective tissue covering of a whole muscle?
A) Epimysium
B) Perimysium
C) Endomysium
D) Sarcolemma
E) Fascia
20. Muscle contraction ends when:
A) ATP is produced
B) Acetylcholine increases
C) Calcium is pumped back into the sarcoplasmic reticulum
D) Actin binds to myosin
E) Glucose is released
21. The area between two Z-lines in a sarcomere is called:
A) M-band
B) H-zone
C) Sarcolemma
D) Sarcomere
E) A-band
22. Which enzyme helps regenerate ATP in muscle cells using creatine phosphate?
A) ATPase
B) Lactase
C) Creatine kinase
D) Glycogen synthase
E) Protease
23. What happens when a muscle fiber receives a stimulus that reaches threshold?
A) It relaxes
B) It produces a partial contraction
C) It contracts fully (all-or-none response)
D) It enlarges
E) It converts to fat
24. What is the term for a single brief contraction of a muscle fiber?
A) Summation
B) Twitch
C) Spasm
D) Reflex
E) Cramp
25. Which type of muscle fiber is most resistant to fatigue and used in endurance activities?
A) Fast glycolytic
B) Slow oxidative
C) Intermediate fibers
D) Myelinated fibers
E) White fibers
26. In muscle contraction, what role does troponin play?
A) Stores calcium
B) Blocks actin binding sites
C) Binds to calcium and exposes actin
D) Breaks down ATP
E) Stimulates nerve endings
27. Which muscle type is branched and interconnected by intercalated discs?
A) Smooth
B) Skeletal
C) Cardiac
D) Voluntary
E) Involuntary smooth
28. What happens to the sarcomere during contraction?
A) It stays the same size
B) It lengthens
C) It shortens
D) It rotates
E) It breaks
29. Which part of the sarcomere remains the same length during contraction?
A) Z-line
B) A-band
C) I-band
D) H-zone
E) Sarcoplasm
30. Which of the following statements is true about skeletal muscle fibers?
A) They are multinucleated and striated
B) They are smooth and uninucleated
C) They are branched
D) They do not respond to stimuli
E) They contract involuntarily
- Questions About the Skeletal System
- Questions About Bones and Joints
- Questions About Skeletal Diseases
Answer Key with Explanations
1. C) Provide movement – Skeletal muscles move bones and body parts.
2. B) Skeletal muscle – Voluntary and striated, attached to bones.
3. B) Calcium ions – Trigger actin-myosin interaction.
4. B) Sarcomere – The functional unit of contraction.
5. D) Myosin – The thick filament that interacts with actin.
6. C) Tendons – Connect muscles to bones.
7. D) Sarcoplasmic reticulum – Stores and releases calcium.
8. D) ATP – Energy source needed for muscle function.
9. C) Connective – It’s a tissue type, not muscle.
10. C) Smooth – Found in the digestive tract, bladder, etc.
11. C) Acetylcholine – Neurotransmitter at neuromuscular junction.
12. D) Sarcolemma – Plasma membrane of muscle fiber.
13. B) Involuntary and striated – Cardiac muscle contracts without conscious control.
14. D) Alternating actin and myosin bands – Cause striations.
15. C) Tetanus – Continuous contraction without relaxation.
16. C) Myosin and actin – Slide past each other during contraction.
17. C) Acetylcholinesterase – Breaks down acetylcholine.
18. D) ATP – Used directly for muscle contraction.
19. A) Epimysium – Surrounds the entire muscle.
20. C) Calcium is pumped back – Contraction stops when calcium is removed.
21. D) Sarcomere – The section between two Z-lines.
22. C) Creatine kinase – Regenerates ATP quickly.
23. C) It contracts fully – Muscle fibers obey the all-or-none law.
24. B) Twitch – A single contraction and relaxation cycle.
25. B) Slow oxidative – Fatigue-resistant, used in endurance.
26. C) Binds to calcium and exposes actin – Initiates contraction.
27. C) Cardiac – Contains intercalated discs.
28. C) It shortens – Sarcomeres shorten during contraction.
29. B) A-band – Stays the same; contains thick filaments.
30. A) They are multinucleated and striated – A hallmark of skeletal muscle.
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